Webb2 feb. 2024 · A comprehensive screen of binding sites of secreted MG53 will be needed to further understand how extracellular MG53 systemically inhibits insulin sensitivity. … Webb1 sep. 2024 · First, MG53 participates in plasma membrane repair of the heart, skeletal muscle, and, other tissues. Second, MG53 is essentially involved in the cardioprotection of cardiac ischemic, preconditioning, …
Cells Free Full-Text MG53, A Tissue Repair Protein with Broad ...
Webb7 nov. 2024 · MG53 has been proven to be involved in repairing cell membrane damage. It has a protective effect on I/R injury in multiple oxygen-dependent organs, such as the heart, brain, lung, kidney, and liver. Recombinant human MG53 also plays a unique role in I/R, … Webb11 jan. 2024 · Recent studies show that Mitsugumin 53 (MG53), a TRIM family protein, plays a key role in repairing cell membrane damage and facilitating tissue regeneration. … mixed commission
Protective role of MG53 against ischemia/reperfusion injury on …
Webb28 nov. 2024 · For instance, short-term intensive exercise increases serum MG53 levels in the mdx dystrophic mice (but not in the wt mice) as a result of muscle injury and subsequent leakage of MG53. 21 Nevertheless, understanding the potential role of MG53 in physiological regulation of insulin sensitivity by physical activity and nutrients requires … Webb21 nov. 2024 · The role of MG53 in repairing cell membrane damage The importance of the cell membrane to the organism is self-evident. It is a barrier to prevent extracellular substances from freely entering the cell, to ensure the relative stability of the intracellular environment, and to make various biochemical reactions proceed in an orderly manner ( … Webb23 nov. 2012 · However, the roles of MG53 in the unique functions of skeletal muscle have not been addressed, although it is known that MG53 is expressed only in skeletal and cardiac muscle. In the present study, MG53-binding proteins were examined along with proteins that mediate skeletal muscle contraction and relaxation using the binding … mixed company jokes