Phytanoyl-coa

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August undefined, 2024

WebbAcyl-CoA is a group of coenzymes that metabolize fatty acids. Acyl-CoA's are susceptible to beta oxidation, forming, ultimately, acetyl-CoA. The acetyl-CoA enters the citric acid cycle, eventually forming several equivalents of ATP. In this way, fats are converted to ATP, the universal biochemical energy carrier. Functions [ edit] Webb27 dec. 2024 · In mammalian catabolic pathways, phytanoyl-CoA undergoes α-oxidation and β-oxidation in peroxisomes and mitochondria (Kohlmeier, 2015; Durrett and Welti, 2024; Gutbrod et al., 2024). In plants, phytanoyl-CoA hydroxylase and 2-hydroxy-phytanoyl-CoA lyase have been localized to peroxisomes and characterized to be the main …

Refsum disease is caused by mutations in the phytanoyl–CoA

Webbphytanoyl-CoA(4−) ChEBI ID CHEBI:57391: ChEBI ASCII Name phytanoyl-CoA(4-) Definition A multi-methyl-branched fatty acyl-CoA(4−) arising from deprotonation of phosphate and diphosphate functions of phytanoyl-CoA . Stars This … http://compbio.biosci.uq.edu.au/mediawiki/index.php/Phytanoyl-CoA_results how to create a listing on mls

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WebbMalonyl-CoA provides 2-carbon units to fatty acids and commits them to fatty acid chain synthesis. Malonyl-CoA is formed by carboxylating acetyl-CoA using the enzyme acetyl-CoA carboxylase. One molecule of acetyl-CoA joins with a molecule of bicarbonate, [1] requiring energy rendered from ATP . Webb10 juli 1997 · Jansen GA, Mihalik SJ, Watkins PA, et al. Phytanoyl-CoA hydroxylase is present in human liver, located in peroxisomes, and deficient in Zellweger syndrome: … Webbphytanoyl-CoA (CHEBI:15538) Services Research Training About us ChEBI Examples: iron* , InChI=1S/CH4O/c1-2/h2H,1H3 , caffeine Advanced Home Advanced Search Browse … how to create a listing presentation

Phytanoyl-coa

Webb1 maj 2000 · In the first step, phytanoyl-CoA is converted to 2-hydroxyphytanoyl-CoA, a reaction catalyzed by phytanoyl-CoA hydroxylase (PhyH) (5, 6). The second step … Webb10 juli 1997 · Phytanic acid, an unusual branched-chain fatty acid (3,7,11,15-tetramethyl-hexadecanoic acid), accumulates in tissues and body fluids of patients with Refsum's disease. 1 The patients are unable to...

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WebbJansen GA, Waterham HR, Wanders RJ: Molecular basis of Refsum disease: sequence variations in phytanoyl-CoA hydroxylase (PHYH) and the PTS2 receptor (PEX7). Hum … WebbIn the peroxisomes, phytanoyl CoA is α-oxidized to PRA, the racemic mixture of PRA is converted by α-methylacyl-CoA racemase (AMACR) to (2S) PRA. After three rounds of β …

Webb2OG-Fe (II) oxygenase family protein belongs to the large and diverse Fe (II)- and 2-oxoglutarate (2-OG)-dependent dioxygenase superfamily and may share a common reaction mechanism, using Fe (II) and the cosubstrate 2-OG in the active site to activate oxygen, resulting in the two-electron oxidation of a target substrate Graphical summary Webbphytanoyl-CoA, and/or directly take up PA (phytanic acid) (or phytanoyl-CoA). The average human intake of PA in the Western diet is 50–100 mg/day, of which about half is …

WebbPhytanic acid (3,7,11,15-tetramethylhexadecanoic acid) is a branched-chain fatty acid present in various dietary products such as milk, cheese and fish. In patients with … Webb1 apr. 2000 · Phytanoyl-CoA hydroxylase is a peroxisomal α-oxidation enzyme that catalyzes the 2-hydroxylation of 3-methyl-branched acyl-CoAs. A polyhistidine-tagged human phytanoyl-CoA hydroxylase was expressed in E. coli and subsequently purified as an active protein.

WebbUnder chlorotic stress or senescence, chlorophyll breakdown results in the release of phytol which can be oxidized to phytenal and further to phytanoyl-CoA. Phytanoyl-CoA …

Webb14 jan. 2011 · phytanoyl-CoA, 2-oxoglutarate:oxygen oxidoreductase (2-hydroxylating) Recommended name. phytanoyl-CoA dioxygenase. Synonyms. PAHX. PhyH. phytanic … microsoft office productcode vindenWebb15 jan. 2008 · Phytanoyl-CoA dioxygenase domain-containing protein 1 By similarity EC number EC:1.14.11.- ( UniProtKB ENZYME Rhea) By similarity Short names Protein PHYHD1 By similarity Gene names Name Phyhd1 Imported Organism names Organism Mus musculus (Mouse) Taxonomic identifier 10090 NCBI Taxonomic lineage microsoft office productcode gratisWebbphytanoyl-CoA C41H74N7O17P3S CID 439640 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, … how to create a listserv cdc outlookIn enzymology, a phytanoyl-CoA dioxygenase (EC 1.14.11.18) is an enzyme that catalyzes the chemical reaction phytanoyl-CoA + 2-oxoglutarate + O2 2-hydroxyphytanoyl-CoA + succinate + CO2 The three substrates of this enzyme are phytanoyl-CoA, 2-oxoglutarate (2OG), and O2, whereas its three products are 2-hydroxyphytanoyl-CoA, succinate, and CO2. how to create a listservWebbphytanoyl-CoA(4−) ChEBI ID CHEBI:57391: ChEBI ASCII Name phytanoyl-CoA(4-) Definition A multi-methyl-branched fatty acyl-CoA(4−) arising from deprotonation of phosphate and … microsoft office productivity applicationshttp://compbio.biosci.uq.edu.au/mediawiki/index.php/Phytanoyl-CoA_dioxygenase_Function microsoft office productivity appsWebb31 aug. 1999 · The enzymes involved are: 1, phytanoyl-CoA synthetase; 2, phytanoyl-CoA hydroxylase; 3, 2-HPCL; 4, branched fatty aldehyde dehydrogenase; and 5, formyl-CoA … microsoft office products 2021